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eGFR calculator online: CKD-EPI 2021 formula without race coefficient

Estimated glomerular filtration rate by the updated CKD-EPI 2021 formula without race coefficient. Used in nephrology, cardiology, and endocrinology for CKD staging and drug dose adjustment in adults.

years

About this calculator

The CKD-EPI 2021 formula is the updated estimated glomerular filtration rate (eGFR) equation for adults aged 18+, recommended by NKF-ASN in 2021 to replace the 2009 version. The key change is removal of the race coefficient, which previously overestimated eGFR in Black patients and delayed referral to transplantation and dialysis. Used in nephrology, cardiology, endocrinology, oncology, and primary care for chronic kidney disease staging, monitoring kidney function trends, nephrotoxic drug dose adjustment, and renal replacement planning. Inputs: serum creatinine, age, sex. CKD stages by eGFR (mL/min/1.73 m²): G1 ≥90 (normal or elevated), G2 60–89 (mild decrease), G3a 45–59 (moderate), G3b 30–44 (moderately severe), G4 15–29 (severe), G5 <15 (kidney failure). The formula is inaccurate at extremes of body mass, acute kidney injury, pregnancy, and in adults over 80 – inulin clearance or cystatin C (CKD-EPI cys 2012) provide more precise eGFR when needed.

Source

Inker LA, Eneanya ND, Coresh J, et al. New Creatinine- and Cystatin C-Based Equations to Estimate GFR without Race. N Engl J Med 2021;385:1737-1749

Formula version: 2021-v1

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