Homeopathic medicines
ATC code: V03AX-ANAFERON (Anti-IFN-γ antibodies in homeopathic dilutions (local code))
The manufacturer claims the use of high dilutions (C12, C30, C50) of affinity-purified antibodies against human interferon-gamma. At these dilutions the number of active molecules approaches or reaches zero (Avogadro's number), making the proposed mechanism of action pharmacologically implausible. Homeopathic products are methodologically incompatible with evidence-based medicine.
Not recommended
Anaferon and its variants for the treatment or prevention of viral URI are not mentioned in international sources. Systematic reviews of homeopathy effectiveness (notably the 2015 report from the Australian National Health and Medical Research Council) found no convincing evidence of clinical efficacy for homeopathic products in any condition.
Not recommended
For herpes infection treatment, not mentioned in international sources. Evidence-based therapy relies on nucleoside analogues.
Not recommended
For the treatment or prevention of influenza in adults and children, not mentioned in international guidelines. Proven antiviral options are neuraminidase inhibitors (oseltamivir, zanamivir) and baloxavir. The cornerstone of prevention is annual vaccination.
Not recommended
— Immune system boosting: Anaferon (homeopathic dilutions of antibodies to human γ-interferon) is actively marketed for «immune boosting» in children and adults with recurrent URIs. Homeopathic dilutions inherently contain less than one molecule of the active substance and carry no biological activity. , , , and international guidelines do not list this product. Evidence-based URI prevention: influenza and pneumococcal vaccination, hand hygiene, and removing secondhand smoke exposure in children.
Safety data during pregnancy are limited; international sources provide no recommendations.
Anaferon (anti-human interferon gamma antibodies in homeopathic dilutions) is evaluated for the following indications with varying evidence strength: Herpes simplex (evidence tier F), Influenza (evidence tier F), Acute respiratory viral infection (evidence tier F). See the full indication matrix with dosing and citations above on this page.
Common side effects of Anaferon (anti-human interferon gamma antibodies in homeopathic dilutions) (≥ 1 in 100): Per manufacturer label — allergic reactions. See the Safety section for uncommon and serious reactions.
Safety data during pregnancy are limited; international sources provide no recommendations.
Anaferon (anti-human interferon gamma antibodies in homeopathic dilutions) is contraindicated in: Lactase deficiency, galactose intolerance, glucose-galactose malabsorption; Age under 1 month (for pediatric formulation); Hypersensitivity. Full list in the Safety section.