4-n-Butylresorcinol

Tyrosinase and TRP-1 inhibitor, known as Rucinol. Works on both melanin synthesis steps, so it delivers stronger depigmentation.

Brightening

Evidence by route

Topical application

Weak evidence. In vitro data, open-label studies, or expert consensus.

In vitro data show a strong effect compared with hydroquinone. Patient studies remain scarce, with part of the data coming from Korean and Japanese groups.

Tolerability and safety

Irritation potential

Low

Allergen risk

Moderate

Pregnancy

Caution

Skin types

Suitable for

NormalOilyCombinationDry

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Frequently asked questions

Is 4-n-Butylresorcinol safe during pregnancy?

4-n-Butylresorcinol should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.

What skin types is 4-n-Butylresorcinol for?

4-n-Butylresorcinol suits: normal, oily, combination, dry.

What is 4-n-Butylresorcinol and what does it do in cosmetics?

Tyrosinase and TRP-1 inhibitor, known as Rucinol.

What's the INCI name for 4-n-Butylresorcinol?

The INCI name is 4-n-Butylresorcinol. It may also appear as: Rucinol.

Published: April 14, 2026 · updated: May 17, 2026