Octinoxate (Ethylhexyl Methoxycinnamate)

INCI: Ethylhexyl Methoxycinnamate

One of the most widely used chemical UVB filters. Banned in Hawaii and Palau due to coral reef harm. Potential endocrine activity is under discussion.

Protection

Evidence by route

Topical application

Limited evidence. One RCT or several controlled studies with limitations.

FDA approved as a UV filter. Systemic absorption confirmed – plasma concentrations exceed the FDA threshold for additional studies. Weak estrogenic activity detected in vitro. Environmental harm to corals is established, leading to bans in several jurisdictions.

Matta MK et al. JAMA. 2019;321(21):2082-2091.
Downs CA et al. Arch Environ Contam Toxicol. 2016;70(2):265-288.

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Caution

Skin types

Suitable for

NormalCombinationOily

Use with caution

Sensitive

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Frequently asked questions

Is Octinoxate (Ethylhexyl Methoxycinnamate) safe during pregnancy?

Octinoxate (Ethylhexyl Methoxycinnamate) should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.

What skin types is Octinoxate (Ethylhexyl Methoxycinnamate) for?

Octinoxate (Ethylhexyl Methoxycinnamate) suits: normal, combination, oily. Use with caution in: sensitive.

What is Octinoxate (Ethylhexyl Methoxycinnamate) and what does it do in cosmetics?

One of the most widely used chemical UVB filters.

What's the INCI name for Octinoxate (Ethylhexyl Methoxycinnamate)?

The INCI name is Ethylhexyl Methoxycinnamate. It may also appear as: Octyl Methoxycinnamate, Octinoxate, 2-Ethylhexyl 4-Methoxycinnamate.

Published: April 13, 2026 · updated: May 18, 2026