Lipophilic derivative of salicylic acid with a caprylic (C8) chain. Unlike plain salicylic acid, it penetrates deeper into sebaceous gland openings thanks to its lipid solubility. Developed by L'Oreal and actively used in the La Roche-Posay Effaclar line. Targets comedones and post-acne marks more than inflammation.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
Several RCTs confirmed effects in acne and post-acne pigmentation. Clinical significance is comparable to plain salicylic acid with better tolerability. Does not replace retinoids or benzoyl peroxide as first-line therapy for severe acne.
Irritation potential
MediumAllergen risk
LowPregnancy
CautionSuitable for
Use with caution
Capryloyl Salicylic Acid should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.
Capryloyl Salicylic Acid suits: oily, combination. Use with caution in: sensitive, dry.
Capryloyl Salicylic Acid has moderate irritation potential. Sensitive skin may show a transient reaction that usually settles with adaptation.
Lipophilic derivative of salicylic acid with a caprylic (C8) chain.
On the Fulton scale 0/5 – non-comedogenic. For acne-prone skin, a rating of 3 or higher suggests choosing an alternative.
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The INCI name is Capryloyl Salicylic Acid. It may also appear as: LHA, Lipohydroxy Acid, Каприлоил салициловая кислота.