Lipopeptide mimicking a collagen fragment. Stimulates fibroblasts to produce collagen and hyaluronic acid. Often combined with palmitoyl tetrapeptide-7 (Matrixyl 3000).
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
Small sponsor-conducted studies demonstrate wrinkle reduction with the Matrixyl 3000 combination. Independent RCTs are scarce. In vitro collagenogenesis activation is shown, but clinical translation is limited by peptide penetration concerns.
Irritation potential
LowAllergen risk
LowPregnancy
UnknownSuitable for
Safety data for Palmitoyl Tripeptide-1 during pregnancy is insufficient. Best avoided when in doubt.
Palmitoyl Tripeptide-1 suits: normal, dry, sensitive, combination.
Lipopeptide mimicking a collagen fragment.
The INCI name is Palmitoyl Tripeptide-1. It may also appear as: Pal-GHK, Пальмитоил трипептид-1, Matrixyl 3000.
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