Second-generation antifungal agent, a zinc pyrithione replacement. Effective against Malassezia – the fungus causing dandruff and seborrheic dermatitis.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
RCTs confirm efficacy for seborrheic dermatitis and dandruff comparable to ketoconazole. Included in medicated shampoos as a safe alternative to zinc pyrithione after its EU restriction.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
Piroctone Olamine is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Piroctone Olamine suits: oily, combination, normal.
Second-generation antifungal agent, a zinc pyrithione replacement.
The INCI name is Piroctone Olamine. It may also appear as: Octopirox.
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