Elemental sulfur in colloidal form. One of the oldest topical anti-acne ingredients. Disrupts hyperkeratosis at follicular openings and provides mild keratolytic and antibacterial effects. Used for acne and seborrheic dermatitis. The characteristic smell limits patient acceptability.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
Topical sulfur 2-10% is included in AAD 2024 guidelines as an option for mild acne and rosacea (combined with sulfacetamide). The effect is modest compared with adapalene or benzoyl peroxide, but it is well tolerated in pregnancy.
Irritation potential
MediumAllergen risk
LowPregnancy
SafeSuitable for
Use with caution
Sulfur is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Sulfur suits: oily, combination. Use with caution in: sensitive, dry.
Sulfur has moderate irritation potential. Sensitive skin may show a transient reaction that usually settles with adaptation.
Elemental sulfur in colloidal form.
On the Fulton scale 0/5 – non-comedogenic. For acne-prone skin, a rating of 3 or higher suggests choosing an alternative.
Published: · updated:
The INCI name is Sulfur. It may also appear as: Colloidal Sulfur, Precipitated Sulfur, Сера.