Ubiquinone (CoQ10)

INCI: Ubiquinone

Coenzyme involved in mitochondrial respiration. Its skin levels decline with age. An antioxidant protecting cell membranes from lipid peroxidation.

Anti-aging Protection

Evidence by route

Topical application

Weak evidence. In vitro data, open-label studies, or expert consensus.

Pilot clinical studies show wrinkle reduction and texture improvement with prolonged use. Antioxidant activity confirmed in vitro. No large independent RCTs. Penetration through the stratum corneum is limited – works better in nano-formulations.

Hoppe U et al. Biofactors. 1999;9(2-4):371-378.

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Safe

Skin types

Suitable for

NormalDrySensitiveCombination

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Frequently asked questions

Is Ubiquinone (CoQ10) safe during pregnancy?

Ubiquinone (CoQ10) is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Ubiquinone (CoQ10) for?

Ubiquinone (CoQ10) suits: normal, dry, sensitive, combination.

What is Ubiquinone (CoQ10) and what does it do in cosmetics?

Coenzyme involved in mitochondrial respiration.

What's the INCI name for Ubiquinone (CoQ10)?

The INCI name is Ubiquinone. It may also appear as: CoQ10, Coenzyme Q10, Убихинон.

Published: April 13, 2026 · updated: April 22, 2026