Metodología y principios editoriales
Cómo Evigrade evalúa medicamentos y componentes cosméticos. Metodología, posición legal, derecho de réplica.
What Evigrade publishes
Todo lo que lee en Evigrade son análisis editoriales basados en guías internacionales, ensayos clínicos aleatorizados y metaanálisis.
How tiers are assigned
Los niveles de evidencia de A a F los asigna el consejo editorial. La metodología es pública y revisamos las evaluaciones cuando aparecen nuevos estudios.
- Tier A – confirmed by ≥2 independent RCTs with clinical endpoints.
- Tier B – one RCT or several controlled studies with limitations.
- Tier C – study data contradict each other
- Tier D – too few or low-quality studies
- Tier F – no evidence of efficacy, or proven inefficacy.
The methodology follows the GRADE approach (Grading of Recommendations Assessment, Development and Evaluation) and the Oxford Centre for Evidence-Based Medicine Levels of Evidence.
What we stand behind
Todas las evaluaciones del sitio son juicios editoriales, no afirmaciones de hecho. No promocionamos ni criticamos a fabricantes concretos: la evaluación se refiere al medicamento por su denominación común internacional, no a una marca concreta.
Evaluative opinions based on public sources are not subject to factual refutation. The editorial evidence rating reflects the editorial board's opinion grounded in publicly available guidelines and studies; it does not contain statements of fact susceptible to verification.
Right of reply
Los fabricantes y titulares de derechos pueden enviar una respuesta motivada a editorial@evigrade.com. La redacción la publica sin editar en un plazo de 14 días hábiles.
A reply must include references to published scientific data. The editorial team reserves the right to append its own commentary without modifying the text of the reply itself.
Corrections and re-evaluation
The editorial team re-evaluates tiers as new randomized controlled trials, meta-analyses, or updated clinical guidelines from international specialist associations appear. Each card displays the date of the last review.
What the tier rates
Ratings apply to the international nonproprietary drug name and a specific indication, not to brands. The same INN receives different tiers for different indications. A tier F for one indication does not imply inefficacy for other indications.
Conflicts of interest
Evigrade is an independent encyclopedia. The editorial team has no direct commercial ties to drug or cosmetics manufacturers. Tier ratings do not depend on marketplace availability, manufacturer advertising budgets, or partnership requests.
Medical disclaimer
Este contenido no reemplaza la consulta con un médico colegiado.
Contact the editorial team
General inquiries: editorial@evigrade.com