Essential omega-6 fatty acid. Key component of type-1 ceramides (Ceramide EOS, EOH) – the foundation of skin barrier function. In acne patients, sebum linoleic acid is often low, contributing to pilosebaceous inflammation. Topical application in acne and dry skin restores the balance. Present in safflower, sunflower, and grape seed oils.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
Linoleic acid deficiency in acne sebum has been confirmed in several studies. Topical use as safflower oil or isolated linoleic acid improves barrier function and reduces comedone activity in small RCTs. The effect is modest but clinically meaningful in a subset of patients.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
Linoleic Acid is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Linoleic Acid suits: normal, dry, combination, oily, sensitive.
Essential omega-6 fatty acid.
On the Fulton scale 1/5 – very low comedogenicity. For acne-prone skin, a rating of 3 or higher suggests choosing an alternative.
The INCI name is Linoleic Acid. It may also appear as: Omega-6, C18:2, Vitamin F.
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