N-Acetyl Glucosamine

INCI: Acetyl Glucosamine

Amino sugar, a precursor of hyaluronic acid. Inhibits tyrosinase, so it lightens post-acne marks and melasma, especially when paired with niacinamide. Also supports skin HA synthesis.

Brightening Moisturizing Anti-aging

Evidence by route

Topical application

Limited evidence. One RCT or several controlled studies with limitations.

Double-blind RCTs with 2% NAG plus 4% niacinamide reduce visible hyperpigmentation significantly better than placebo over 8–10 weeks. Well tolerated, unlike hydroquinone.

Bissett DL et al. J Cosmet Dermatol. 2007;6(1):20-26.
Kimball AB et al. Br J Dermatol. 2010;162(2):435-441.

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Safe

Skin types

Suitable for

NormalDryOilyCombinationSensitive

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Frequently asked questions

Is N-Acetyl Glucosamine safe during pregnancy?

N-Acetyl Glucosamine is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is N-Acetyl Glucosamine for?

N-Acetyl Glucosamine suits: normal, dry, oily, combination, sensitive.

What is N-Acetyl Glucosamine and what does it do in cosmetics?

Amino sugar, a precursor of hyaluronic acid.

What's the INCI name for N-Acetyl Glucosamine?

The INCI name is Acetyl Glucosamine. It may also appear as: N-Acetyl Glucosamine, NAG, GlcNAc.

Published: April 27, 2026 · updated: April 27, 2026