Panthenol (Provitamin B5)

INCI: Panthenol

Alcohol analogue of pantothenic acid. Penetrates skin and converts to pantothenic acid, required for coenzyme A synthesis. Accelerates healing and reduces irritation.

Moisturizing Soothing Barrier repair

Evidence by route

Topical application

Proven efficacy. Two or more independent RCTs with instrumental endpoints.

RCTs confirm accelerated wound healing and superficial burn recovery, reduced erythema after laser procedures, and improved barrier function. Widely used after cosmetic procedures as a post-procedural care ingredient.

Ebner F et al. J Dermatolog Treat. 2002;13(4):173-178.
Wollina U et al. Skin Pharmacol Physiol. 2012;25(6):302-308.

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Safe

Skin types

Suitable for

OilyCombinationSensitiveNormalDry

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Combinations with other ingredients

Works well with

RetinolРетинол

Panthenol softens retinol adaptation in the first weeks. Reduces redness and flaking without blocking the main effect.

Frequently asked questions

Is Panthenol (Provitamin B5) safe during pregnancy?

Panthenol (Provitamin B5) is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Panthenol (Provitamin B5) for?

Panthenol (Provitamin B5) suits: oily, combination, sensitive, normal, dry.

What is Panthenol (Provitamin B5) and what does it do in cosmetics?

Alcohol analogue of pantothenic acid.

What's the INCI name for Panthenol (Provitamin B5)?

The INCI name is Panthenol. It may also appear as: D-Panthenol, Pro-Vitamin B5, Dexpanthenol.

Published: April 13, 2026 · updated: May 17, 2026